Microbial Menace and Miracle: The Double-Edged Sword of Infection and Immunity
Articles

Diverse MIC Determination Methods: Implications for Effective Infection Management

Suraj Jyote
Department of Biotechnology, School of Life Sciences, Swami Vivekananda University, Barrackpore, West Bengal—70012
Priyajit Banerjee
Department of Biotechnology, School of Life Sciences, Swami Vivekananda University, Barrackpore, West Bengal—700121
Debanshu Sharma
Department of Biotechnology, School of Life Sciences, Swami Vivekananda University, Barrackpore, West Bengal—700121
Suranjana Sarkar
Department of Microbiology, School of Life Sciences, Swami Vivekananda University, Barrackpore, West Bengal – 700121

Published 2025-12-01

Keywords

  • Antimicrobial resistance,
  • Broth dilution,
  • E-test,
  • MIC testing,
  • Microbial resistance

How to Cite

Jyote, Suraj, et al. “Diverse MIC Determination Methods: Implications for Effective Infection Management”. Swami Vivekananda University Press, Dec. 2025, pp. 296-02, https://swamivivekanandauniversitypress.com/index.php/svup/article/view/158.

Abstract

Minimum Inhibitory Concentration (MIC) is a fundamental parameter in microbiology and antimicrobial research, used to determine the lowest concentration of an antimicrobial agent required to inhibit the visible growth of a microorganism. Various MIC determination methods, including broth dilution, agar dilution, gradient diffusion (E-test), and automated systems, provide valuable insights into antimicrobial efficacy and resistance patterns. Each technique has unique advantages in terms of accuracy, cost, scalability, and applicability in clinical, research, and pharmaceutical settings. MIC testing plays a crucial role in guiding antimicrobial therapy, monitoring resistance trends, and supporting drug development. Understanding the strengths and limitations of different MIC techniques helps optimize their application in laboratory and clinical practices, ensuring effective infection control and antimicrobial stewardship.

DOI - https://doi.org/10.65525/SVUP.9788198471956.2025.296-302